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Binghamton (Broome County) has been a post office since 1830. A nicely struck example on a very clean Ladies cover.
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Cape Vincent (Jefferson County) has had 2 periods of operation: 1817 - 1861, and then again from 1861 to the current day. Again, a very nicely struck example on a watermarked type of paper.
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Oramal was a post office in Allegany County in 1850, and again in 1852 - 1968.